Current treatments for chronic pain have limited benefit. We describe a resilience intervention for individuals with chronic pain which is based on a model of viewing chronic pain as dysregulated homeostasis and which seeks to restore homeostatic self-regulation using strategies exemplified by survivors of extreme environments. The intervention is expected to have broad effects on well-being and positive emotional health, to improve cognitive functions, and to reduce pain symptoms thus helping to transform the suffering of pain into self-growth. A total (...) of 88 Veterans completed the pre-assessment and were randomly assigned to either the treatment intervention or control. Fifty-eight Veterans completed pre- and post-testing. The intervention covered resilience strengths organized into four modules: engagement, social relatedness, transformation of pain and building a good life. A broad set of standardized, well validated measures were used to assess three domains of functioning: health and well-being, symptoms, and cognitive functions. Two-way Analysis of Variance was used to detect group and time differences. Broadly, results indicated significant intervention and time effects across multiple domains: Pain decreased in present severity [F = 5.02, p < 0.05, η2p = 0.08], total pain over six domains [F = 14.52, p < 0.01, η2p = 0.21], and pain interference [F = 6.82, p < 0.05, η2p = 0.11]; Affect improved in pain-related negative affect [F = 7.44, p < 0.01, η2p = 0.12], fear [F = 7.70, p < 0.01, η2p = 0.12], and distress [F = 10.87, p < 0.01, η2p = 0.16]; Well-being increased in pain mobility [F = 5.45, p < 0.05, η2p = 0.09], vitality [F = 4.54, p < 0.05, η2p = 0.07], and emotional well-being [F = 5.53, p < 0.05, η2p = 0.09] Mental health symptoms and the cognitive functioning domain did not reveal significant effects. This resilience intervention based on homeostatic self-regulation and survival strategies of survivors of extreme external environments may provide additional sociopsychobiological tools for treating individuals with chronic pain that may extend beyond treating pain symptoms to improving emotional well-being and self-growth.Clinical Trial Registration: Registered with ClinicalTrials.gov. (shrink)

BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

In this stimulating book, six leading philosophers--Karl-Otto Apel, Robert Brandom, Karsten Harries, Martha Nussbaum, Barry Stroud, and Allen Wood--consider the nature of philosophy. Although each of them has a unique perspective, they all seem to agree that philosophy seeks to uncover hidden assumptions and concepts in order to expose them to critical scrutiny. It is thus entirely fitting that philosophers should examine their own assumptions about the nature of their discipline. As they delve into the nature of philosophy, the (...) authors address many fascinating subjects: what makes philosophy different from natural science, religion, and other branches of the humanities; whether philosophy can contribute to political transformation, and if so, how; whether there can ever be an "end of philosophy"; and more. The editors' introduction ties together the contributors' diverse perspectives by noting common themes, similarities, and differences. (shrink)

L’article dont nous présentons ici la traduction fait partie des principaux textes qui ont, au début des années 1990, remis au goût du jour la perspective cosmopolitique. C’est ce caractère rénovateur qui motive notre choix de publication. Depuis la rédaction de cet article, Martha Nussbaum a régulièrement écrit sur la notion de cosmopolitisme et sur son articulation avec l’idée de patriotisme, précisant sa pensée sur ce point. Son article le plus récent sur cette question précise est « Toward a (...) globally sensitive patriotism » (paru dans la revue Dædalus, CXXXVII, n? 3, 2008, p. 78-93). (shrink)

The wave-mechanical treatment of the valence bond, by Walter Heitler and Fritz London, and its ensuing foundational importance in quantum chemistry has been traditionally regarded as the basis for the argument that chemistry may be theoretically reduced to physics. Modern analyses of the reductionist claim focuses on the limitations to achieving full reduction in practice because of the approximations used in modern quantum chemical methods, but neglect the historical importance of the chemical bond as a chemical entity. This paper re-examines (...) these arguments with a study of the development of the valence bond by chemist Gilbert Lewis within a chemically autonomous framework, and its extension by Linus Pauling using Heitler and London’s methods. Here, we see that the chemical bond is best described as a theoretical synthesis or physico-chemical entity, to represent its full interdisciplinary importance from the philosophical and historical perspectives.Keywords: Reductionism; Chemical bond; Linus Pauling; Gilbert Lewis; Heitler–London; Chemical. (shrink)

Biotechnology increases commercialization of food production, which competes with food for home use. Most people in the world grow their own food, and are more secure without the mediation of the market. To the extent that biotechnology enhances market competitiveness, world food security will decrease. This instability will result in a greater gap between rich and poor, increasing poverty of women and children, less ability and incentive to protect the environment, and greater need for militarization to maintain order. Therefore, biotechnology (...) should be discouraged. An active program to protect and strengthen local food production and to decrease reliance on industrial agriculture should be promoted. (shrink)

Franck L. B. Meijboom: Problems of Trust: A Question of Trustworthiness Content Type Journal Article DOI 10.1007/s10806-010-9300-4 Authors Martha L. Henderson, Master of Environmental Studies Program, The Evergreen State College, Olympia, WA 98505, USA Journal Journal of Agricultural and Environmental Ethics Online ISSN 1573-322X Print ISSN 1187-7863.

The Healer's Art curriculum is one of the best-known educational strategies to support medical student professional identity formation. HART has been widely used as an elective curriculum. We evaluated students’ experience with HART when the curriculum was required. All one hundred eleven members of the class of 2019 University of New Mexico School of Medicine students were required to enroll in HART. We surveyed the students before and after the course to assess its self-reported impact on key elements of professional (...) identity formation such as empathy towards patients and peers, commitment to service, and burnout. A majority of students reported positive effects of the course on their empathy towards other students. This finding was significantly associated with self-reported willingness to have elected the course had it not been required. One-half of respondents reported positive effects on their empathy towards future patients. At least one-quarter to one-third of respondents reported positive influences on commitment to service, conceptions about being a physician, and self-perceived burnout. Students report benefits on their professional identity formation after participating in a required course on humanism. Empathy-building among peers is one valuable outcome of such curricula. (shrink)

The gauge compensation fields induced by the differential operators of the Stueckelberg-Schrödinger equation are discussed, as well as the relation between these fields and the standard Maxwell fields; An action is constructed and the second quantization of the fields carried out using a constraint procedure. The properties of the second quantized matter fields are discussed.

It is well known that when resolution occurs in the stichic iambics and trochaics of tragedy word-end is not found between the two shorts so produced: w or, more accurately, that the first short of resolution must not be the last syllable of a polysyllabic word. Moreover, the syllables in resolution most often form part of the same word as the following short or anceps, e.g.: Ion 1143.

As in literature poetry precedes prose, so in poetry a special and ‘heightened’ diction seems to precede everyday language. Mr.T.S.Eliot has put it thus: ‘Every revolution in poetry is apt to be, and sometimes to announce itself as, a return to common speech.’ How does this apply to Greek and Latin ? There are objections to considering words in isolation from this point of view, since neutral ones are apt to go now grey, now purple, according to their company; but (...) if we do not do so, we deny ourselves the only considerable method of investigation that is still open to us. Again, we must recognize that most poems are composed largely of ordinary words, though these are often used in a way that is not ordinary. (shrink)

Some of the problems associated with the construction of a manifestly covariant relativistic quantum theory are discussed. A resolution of this problem is given in terms of the off mass shell classical and quantum mechanics of Stueckelberg, Horwitz and Piron. This theory contains many questions of interpretation, reaching deeply into the notions of time, localizability and causality. A proper generalization of the Maxwell theory of electromagnetic interaction, required for the well-posed formulation of dynamical problems of systems with electromagnetic interaction is (...) discussed, and some of the significance of recently found (classical) relativistic chaotic behavior is pointed out. Many results of a technical nature have been achieved in this framework; in this paper, some of these are reviewed, but I shall concentrate on a discussion of the basic ideas and foundations of the theory. (shrink)

The elements which every schoolboy learns on beginning Latin Verse Composition include a number of rules which seem arbitrarily designed to make the game harder. In hexameters, he is told, he must have a masculine caesura either in the third foot or in the second and fourth, and end normally with a disyllabic or a trisyllable; in pentameters he must end with a disyllabic; and in neither line may a single monosyllable stand at the end. Rarely, in my experience, is (...) any reason given him by way of redress, and he will search for one in vain in most of the school text-books, in introductions like Postgate's to Tibullus and Propertius, and in histories of Latin literature like Wight Duff's and Mackail's. This reticence may be due to the dissensions of experts on this subject and on the subject of Latin accentuation in general, but the theory that predominates in England, among those who hold a theory at all, explains so many of the phenomena that it deserves to be more widely and precisely known. The most detailed exposition of it is by E. H. Sturtevant, who summed up his analyses in a pair of articles in the Transactions of the American Philological Association in 1923–4. While his careful work is invaluable as marshalling the statistics and evidence, it errs on the side of excessive minuteness, and leaves room not merely for some additions, but for a different kind of treatment concerned less with bare statistics and more with poetic principles and historical development. Since Latin Verse Composition plays such an important part in English higher classical education, it seems desirable that a less technical and more accessible account should be available for English readers. Such an account I attempt to give here, keeping separate as far as possible the exposition and the consideration of the criticisms and rival theories that have been advanced. (shrink)

Gilbert Ryle in The Concept of Mind pronounced the “official doctrine” regarding the nature of the mind and the body as “hailing chiefly from Descartes.” That doctrine, anathematized by Ryle as “the dogma of the ghost in the machine,” is said to hold that every human being is composed of a body and a mind, that the body is physical whereas the mind is not, and that the mind may continue to exist when the body is destroyed. Ryle’s famous attack (...) on the official doctrine has undoubtedly stimulated Cartesian studies, both in those who wish to understand Descartes better in order to make the defense of the doctrine more effective and in those who wish to attack it, sometimes even with arguments which Ryle himself would have rejected. Occasionally, one reads a reference to “Platonic dualism,” not so much as a clearly defined alternative to Cartesian dualism but rather as an inchoate or loose version of Descartes’ doctrine. A recent exception is Richard Rorty who in the first chapter of his book Philosophy and the Mirror of Nature has insisted on the difference between the Platonic and the Cartesian positions, although it should perhaps be added that his hostility to the former is if anything greater than his hostility to the latter. Without suggesting that there are not obvious similarities in the Platonic and Cartesian versions of dualism, it will perhaps be useful to try to penetrate beneath the slogans in order to get a clearer picture of the arguments which impelled Plato to hold a position the strangeness which was evident even to his contemporaries. (shrink)

In C.Q. xliii , p. 39, Mr. J. H. Quincey quotes the opening lines of Catalepton 5 as, Ite hinc,-inanes, ite, rhetorum ampullae, inflata rhoso* non Achaico verba, and adds, ‘the second line is corrupt and no satisfactory emendation has been proposed’. The MS. readings are: rhorso B, roso Mu, om. in lacuna Ar. In face of these voces nihili many have fallen back on the rore of the Aldine edition of 1517. But this does not really help, for one (...) does not inflate with dew: orators are not dew-bags, but wind-bags. It occurred to me some years ago that what is needed is some word meaning breath or wind to go with inflata, and that in view of the rh in rhorso it was probably a Greek word which a scribe had failed to recognize. I conjectured οζ, and found subsequently that this had been proposed by K. Münscher in Hermes, xlvii , pp. 153–4. οȋζος used of any rushing sound, is applied to speech by Philostratus , and by Pollux . It is easy to see how rhoezo could degenerate into rhoeso-rhoso-roso. (shrink)

In this paper we show that the prime ideal space of an MV-algebra is the disjoint union of prime ideal spaces of suitable local MV-algebras. Some special classes of algebras are defined and their spaces are investigated. The space of minimal prime ideals is studied as well.